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Deciphering the Role of V88L Substitution in NDM-24 Metallo-β ... - MDPI

This study characterizes the role of the V88L substitution in NDM-24 and provides insight about the NDM variants evolution. (A) Thermal stability melting curves.

Description: Deciphering the Role of V88L Substitution in NDM-24 ...

Figure 1. New Delhi metallo-β-lactamase-1 (NDM-1) variants phylogenetic analysis. Phylogenetic groups were differently coloured: For example, the NDM-24 cluster is coloured in green. - "Deciphering the Role of V88L Substitution in NDM-24 metallo-β-lactamase"

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The V88L substitution occurred in the β-strand and low β-sheet content in the secondary structure, as evidenced by the CD analysis data. In conclusion, the V88L substitution increases the...

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